Fibrosarcoma

ICD-O:8810/3

Fibrosarcoma of the s inonasal tract occurs across a wide age range, most commonly causing obstruction or epistaxis. The histologic appearance is that of a spindle cell lesion, with fascicles or bundles of neoplastic cells intersecting at various angles, sometimes with a herringbone pattern. Most sinonasal fibrosarcomas have a low-grade appearance, with moderate cellularity and a low mitotic rate [111]. In accordance, the behaviour is more often characterised by repeated local recurrences, while distant metastases are rare. The differential diagnosis includes desmoid fibromatosis, leiomyosar-coma, nerve sheath tumours, spindle cell carcinoma and melanoma.

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