The special anatomic framework of Reinke's space is considered essential for the development of a group of so-called exudative benign lesions of the vocal cords, including Reinke's oedema (RO), vocal cord polyps (VCPs) and nodules (VCNs) [177, 179, 181, 238, 308]. Each of three entities has its own clinical and morphological specificities , but most of them overlap. The common basic pathogenetic mechanism is blood vessel injuries with accumulation of oedematous fluid in Rein-ke's space [85, 308].
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