Congenital Glaucoma

Glaucoma due to congenital malformation is rare. Associations with systemic disorders like neurofibromatosis [8, 84, 130] and Sturge-Weber syndrome [18, 19] have been described. A malformation of the trabecular mesh-work (goniodysgenesis) or persistence of embryonic tissue in the chamber angle causes an outflow obstruction. The corneoscleral envelope of the infant is distensible, so that a raised intraocular pressure can produce an enlargement of the globe (buphthalmos). A hypercellular trabecular meshwork with hyaloid degeneration is the best visible histopathological finding in those specimens [133].

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