And Prognosis

Wide surgical excision, alone or with radical neck dissection is the most successful treatment for SpCC. Radiation therapy is generally considered less effective.

The prognosis is similar to that for conventional SCCs and depends on the location of the tumour and the stage: glottic SpCCs have a good prognosis, while SpCCs in the oral cavity and paranasal sinuses behave more aggressively [29, 31]. Prognostic significance has been also suggested for the gross appearance of the tumour, i.e. polypoid lesions having a better prognosis than flat ul-cerative tumours [375].

The reported 5-year survival is between 63 and 94%; the overall lethality of the tumour is 30-34% [29, 356].

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