Achieving good glycaemic control is important for all patients with ESRF as this can retard the progression of the microvascular and macrovascular complications (5). Good glycaemic control at the start of dialysis has also been shown to improve mortality risk. For patients on continuous ambulatory peritoneal dialysis (CAPD) hyperglycaemia increases circulating advanced glycation end products (AGE), which have been implicated in causing endothelium and peritoneal membrane damage with loss of ultrafiltration capacity. Good glycaemic control reduces thirst, which in turn helps to reduce fluid associated weight gain.
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