Mus musculus

Various bacteria, protozoa, fungi, and helminths

Physical barriers, microbial flora, genetically determined infection susceptibility, innate and adaptive immune system

an experimental model of human XLA. The impaired B-lymphocyte development results in marked reductions in the serum levels of all three major classes of immunoglobulins. Affected patients suffer from frequent infections with enteroviruses, Salmonella enterica, Campylobacter spp., Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, and P. aeruginosa [61].

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