Further Reading


Bodmer, Walter, and Robin McKie. The Book of Man. New York: Scribner, 1994.

Describes recent discoveries about human genetics, including the finding of the Huntington's disease gene.

Cook-Deegan, Robert. The Gene Wars: Science, Politics, and the Human Genome. New York: W. W. Norton, 1994.

Discusses scientific and political conflicts during the early stages of the Human Genome Project and the ethical issues this research raises, including the risk of genetic discrimination.

Glimm, Adele. Gene Hunter: The Story of Neuropsychologist Nancy Wexler. Danbury, Conn.: Franklin Watts, 2005. Biography of Wexler for young adults.

Wexler, Alice. Mapping Fate. New York: Random House/Times Books, 1995.

Memoir written by Nancy Wexler's older sister describes the loss of their mother to Huntington's disease and the medical research to locate the disease-causing gene that Nancy Wexler and her father, Milton, sponsored.

Wexler, Nancy. "Clairvoyance and Caution: Repercussions from the Human Genome Project." In The Code of Codes, edited by Daniel J. Kevles and Leroy Hood. Cambridge, Mass.: Harvard University Press, 1992.

Long essay by Wexler describes the search for the Huntington's gene and considers the ethical and social issues raised by genetic testing.


Gusella, J. F., et al. "A Polymorphic DNA Marker Genetically Linked to Huntington's Disease," Nature, 17 November 1983, pp. 234-238.

Scientific paper reporting location of a RFLP marker usually inherited with the gene that causes Huntington's disease.

Huntington's Disease Collaborative Research Group. "A Novel Gene Containing a Trinucleotide Repeat That Is Expanded and Unstable on Huntington's Disease Chromosomes," Cell 72 (March 26, 1993): 971-983.

Scientific paper describing location of the gene that causes Huntington's disease and identification of the gene's defect.

Murray, Mary. "Nancy Wexler," New York Times Magazine, 13 February 1994, p. 28.

Extensive article on Wexler and her work, written soon after the discovery of the Huntington's gene.

Picker, Lauren. "All in the Family," American Health, 13 (March 1994): 20-23.

Profile of Wexler and description of her research.

"A Tale of Pain and Hope on Lake Maracaibo," Business Week, 5 June 2000, pp. 20E/O.

Describes Wexler's research on a large Venezuelan family in which Huntington's disease is common.

"Venezuelan Kindreds Reveal Genetic and Environmental Factors Influence Onset of Huntington's Disease." Columbia University Medical Center press release. March 2, 2004. Available online. URL: http://www.hdfoundation.org/news/20040302-CUMC.htm. Accessed on November 12, 2004.

Describes research by Nancy Wexler showing that certain factors can delay the onset of Huntington's disease.

"Wexler, Nancy S." Current Biography Yearbook 1994, 607-611. New York: H. W. Wilson, 1994.

Profile of Wexler, written soon after the discovery of the Huntington's gene, summarizes other material written about her.

Web Sites

Hereditary Disease Foundation. This organization, founded by Nancy Wexler and her father, Milton, in 1968, sponsors research on Huntington's disease and related disorders. Their site includes news briefs on recent discoveries about the disease and possible treatments for it. www.hdfoundation.org. Accessed on January 6, 2005.

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