H

Haloperidol

P450, 61

Herpes Simplex Virus-tyrosine kinase gene, 83

[3H]-estradiol rbOSCP, 287-288 Heterosexual exposure neurosteroid levels, 6 Hippocampal formation

Magnetic resonance imaging (MRI), 114 Hippocampal interneurons, 236, 237 Hippocampal neurons electrophysiological studies, 175 Hippocampus estrogen sensitivity, 236, 237, 238 growth factors, 243 sex hormones, 235 synaptogenesis, 240 Hormonal steroid astroglia, 256 259 metabolism nervous system, 97—115 Hormone action brain, 234 Hormone-stimulated steroidogenesis

PBRs. 80 81 5-HT3 receptors, 137, 138 Hydroperoxide pathway, 11 Hydroxylase 5alpha, 55 7alpha, 13, 14 17alpha, 54t, 57, 58 3beta, 55

11 beta, 54t, 57, 58 Hydroxvl group, 3alpha esterification and oxidation, 144 Hydroxy steroid dehydrogenase (HSD)

3beta. 13, 38, 39 Hydroxysteroid ox i do reductase (HOR)

pathways, 99f, 111 f 20alpha, 14 11 beta, 41. 113, 114

pathways, 99f, 11 If 17beta, 39, 40, 112, 1 13 pathways, 99f, 111 f Hypothalamic astroglia steroids

IGF-1, 262, 263 Hypothalamic neurons estradiol

estrogen receptors, 260, 261 Hypothalamus gonadal hormone action, 234, 235

Imipramine P450, 61 Immunohistochemical localization

P4502D4, 61 Immunohistochemistry

P450SCC, 56-57 Infradian rhythms neurosteroid levels, 5, 6 Inner mitochondrial megachannel (IMC), 78 Insulin-like growth factor I (IGF-1) estradiol hypothalamic neurons, 260 estrogen, 260

gonadal hormones, 259, 260 hypothalamic neurons estrogen receptors, 260, 261 steroids hypothalamic astroglia, 262, 263 tanycytes, 262, 263 Insulin-like growth factor I (IGF-1)1 receptors astroglia estradiol, 261 Ion channels neurotransmitter receptors steroid modulators, 168t-174t transmitter-gated neurosteroids selectivity, 135-138 Ion flux assays nAChR, 212 Ionotropic glutamate receptors, 136, 137 modulation neuroactive steroids, 167-185 Isocaproic acid, 29

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