Lymphatics are an integral part of the tissue transport system and the site of adipogenesis and immunological control. All organs, with the exception of the brain, tendons, and ligaments, have a lymphatic system. They carry fluids containing a wide variety of organic and inorganic molecules, colloids, and cells. In tumors, lymphatics have special significance as one of the main pathways for metastatic cells. Lymphatic fluid moves unidirectionally from the tissue through afferent channels toward strategically located lymph nodes. After passage through the lymph node, lymphatic fluid is carried through confluent efferent channels into the two central lymphatic ducts and returned through the subclavian junctions back into the venous circulation. In the following review, we will describe the main micro-anatomical, cellular, and molecular features of microlym-phatics common among different tissues and organs, and we will outline mechanisms that serve the transport of lymph fluid and lymph angiogenesis.
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This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.