The endothelial cells (ECs) lining the walls of blood vessels in the microcirculation have a number of important functions. These include contributions to tissue structure and growth, and mediation of leukocyte recruitment from the circulation into the tissue, either for homeostasis or during inflammation. ECs can express many structures on their luminal surfaces including adhesion molecules (AMs) that are key players in leukocyte infiltration from the circulation to the tissue. This chapter will focus on the description of AMs and their ligands that mediate leukocyte-EC circulating interactions, relating to cell recruitment. Further, it will address tissue-specific expression of AMs and their related functions, particularly in the lung and pulmonary circulation [1].

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Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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