Figure 2 Integrin signaling cascades during angiogenesis. Various integrins, extracellular matrix proteins, and receptor tyrosine kinases with roles in endothelial cell function are shown. Pink lettering indicates endogenous inhibitors of integrin-mediated angiogenesis. Orange lettering indicates blocking antibodies or peptide antagonists that inhibit integrin function. Lines with double-headed arrows indicate direct physical connections between proteins. Double-headed ball-ended lines denote signaling cross-talk between receptors. (see color insert)

dation of the proangiogenic factor fibronectin generates the angiogenesis inhibitor anastelin.

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Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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