Federica Marelli Berg

Imperial College, London

Lymphocyte recirculation and the localized recruitment of antigen-specific T cells to sites of inflammation are critical to the surveillance and effector functions of the immune system. A tightly regulated series of molecular interactions with the microvascular endothelium (extravasation) allows T lymphocytes to continuously recirculate from the bloodstream into lymphoid and nonlymphoid tissue scanning for their cognate antigen. During these frequent encounters the endothelium itself has the opportunity to display antigen to transiting T lymphocytes with the potential to modify their functions.

Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

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