The peritoneal transport of low-molecular-weight solutes has traditionally been investigated with the peritoneal equilibration test (PET). Parameters that can be calculated from such a standardized test are the mass transfer area coefficient (MTAC) of a solute, its dialysate-to-plasma (D/P) ratio, and the clearance of that solute. The MTAC or the D/P ratio is determined mainly by the peritoneal vascular surface area, because this solute transport is the major process in PD. It is suggested that under basal circumstances only about 25 to 50 percent of the peritoneal capillaries are perfused. Based on D/P creatinine, practically used as small solute transport rate, patients have been classified into four transport categories: low, low-average, high-average, and high.
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This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.