Normal

Representative mid-striatal transaxial FD-PET images through the caudate and putamen of a healthy volunteer and patients with PD of moderate severity and MSA. Note the relative sparing FD uptake in the caudate of the PD patient compared with the uniform reduction in the caudate and putamen of the MSA patient. sive to L-dopa treatment (presumed diagnosis of striatonigral degeneration) was compared with eight PD patients. As in the earlier study, FD uptake in the putamen was equally...

Info

This patient with a history of mesothelioma underwent FDG-PET imaging to assess the degree of disease activity in the right pleural structures. The images demonstrate abnormally increased radiotracer uptake around the right lung, involving all pleural surfaces as well as the minor fissure suggestive of malignant mesothelioma. No definite evidence of locoregional or distant metastasis was observed on these images. Fig. 7. This patient with a history of mesothelioma underwent FDG-PET...

Fmiso

FMISO image of a patient with a non-small cell lung cancer. Fig. 14. FMISO image of a patient with a non-small cell lung cancer. ceutical has rapid washout from normoxic areas. It is a useful imaging agent for identifying regions of tissue that have higher levels of reducing agents, such as NADH, as a consequence of hypoxia. There is ample evidence in the literature that the concentration of NADH is increased under extended hypoxic conditions. This mechanism is distinct from that for...

Ayse Mavi MDa Paras Lakhani BAa Hongming Zhuang MD PhDa Naresh C Gupta MDb Abass Alavi MDa

ADivision of Nuclear Medicine, Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA bFrederick Imaging Centers, 46 B Thomas Johnson Drive, Frederick, MD 21702, USA Radiologic imaging modalities play a critical role in the diagnosis and the overall management of many pulmonary disorders, including solitary pulmonary nodules, lung cancer, and pleural diseases. In these conditions, a correct and timely diagnosis is essential and can...

Norbert E Avril MDa Wolfgang A Weber MDb

ADivision of Nuclear Medicine, Department of Radiology, University of Pittsburgh Medical Center, 200 Lothrop Street, b'Department of Medical and Molecular Pharmacology, University of California at Los Angeles, 10833 Le Conte Avenue, AR 193 CHS, Los Angeles, CA 90095, USA The treatment of cancer patients is constantly evolving, striving for more efficient therapies with fewer side effects. Chemotherapy and radiation therapy are still the major therapeutic modalities besides surgery. Because a...

Alan J Fischman MD PhDab

ADivision of Nuclear Medicine, Department of Radiology, Massachusetts General Hospital, 32 Fruit Street, Boston, MA 02114, USA b'Department of Radiology, Harvard Medical School, Boston, MA, USA Parkinson's disease (PD) is a chronic and progressive neurodegenerative condition that is characterized clinically by tremor at rest, rigidity, bradykinesia, and postural instability. The primary pathologic features of PD are degeneration of striatal dopamine neurons and their terminal fields in the...