Steroid Hydroxylation Microbial Steroid Biotransformations Using Cytochrome P450 Enzymes 155

Matthias Bureik and Rita Bernhardt

6.1 Introduction 155

6.2 Cytochrome P450-Dependent Steroid Hydroxylase Systems 156

6.3 Native Microorganisms in Steroid Biotransformation 159

6.3.1 11a-Hydroxylation 160

6.3.2 11P - Hydroxylation 161

6.3.3 16 a-Hydroxylation 162

6.3.4 Conclusions 163

6.4 Genetically Modified Microorganisms in Steroid Biotransformation 163

6.4.1 Soluble Cytochromes P450 164

6.4.2 Membrane-Bound Cytochromes P450 166

6.5 Synopsis and Concluding Remarks 170 References 171

Heal Yourself With Qi Gong

Heal Yourself With Qi Gong

Qigong also spelled Ch'i Kung is a potent system of healing and energy medicine from China. It's the art and science of utilizing breathing methods, gentle movement, and meditation to clean, fortify, and circulate the life energy qi.

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