ALPF Medical Research

Name

Preservative

Active Ingredients

Notes

Boston® One Step Liquid Enzymatic Cleaner PROFREE/GP® Weekly Enzymatic Cleaner

Preservative free Edetate disodium

Subtilisin Papain

Not to be dissolved in distilled water

C. Daily Protein Remover

Name

Preservative

Notes

Opti-Free® Supraclens® Daily Protein Remover

Preservative free

Not for direct use in eye

Name

Preservative

Notes

AOSEPT Clear Care Cleaning & Disinfection Solution

3% Hydrogen peroxide

E. Storage & Disinfection

Name

Preservative

Notes

AQuify Long Lasting Comfort Drops

Not available

Blink contacts

Not available

CIBA Vision Lens Drops

Not available

Clerz Plus Lens Drops

Not available

Complete Blink-N-Clean Lens Drops

Not available

BOSTON® Rewetting Drops

Edetate disodium 0.05% &

Chlorhexadine gluconate 0.006%

CLARIS™ Rewetting Drops

Hydroxyethyl cellulose, polixetonium chlorine 0.006%

Optimum by Lobob Wetting & Rewetting Drops

Edetate disodium, sorbic acid, benzyl alcohol

Perma-Cote

Benzalkonium chloride 0.002%

Sereine™ Wetting Solution

Edetate disodium 0.1% &

Benzalkonium chloride 0.01%

TheraTears Contact Lens Comfort Drops

Not available

BOSTON Simplicity® Multi-Action Solution

Edetate disodium 0.05%,

Polyaminopropyl biguanide 0.0005%,

Chlorhexadine gluconate 0.003%

BOSTON Simplus Multi-Action Solution

Not available

Lens Comfort Multipurpose Solution

Not available

Optimum by Lobob C/D/S

Not available

Unique-pH Multi-Purpose Solution

Not available

Legend: + =

sensitive

baci

=

bacitracin

gati

=

gatifloxacin

oflox

= ofloxacin

o =

not sensitive

CAM

=

chloramphenicol

gent

=

gentamicin

poly/trimeth

= polymyxin B/trimethoprim

i =

intermediate activity

cipro

=

ciprofloxacin

levo

=

levofloxacin

sulfa

= sulfacetamide

? =

unknown

ceph

=

cephazolin

norflox =

norfloxacin

tetra/poly

= tetracycline/polymyxin B

erythro =

erythromycin

moxi

=

moxifloxacin

tobra

= tobramycin

FR = fluoroquinolone resistant

vaneo

= vancomycin

polymyxin poly/

tetra/

baci

cephazolin

CAM

cipro

erythro gati

gent

levo

moxi

norflox oflox

B

trimeth

sulfa

poly

tobra

vaneo

Staph aureus (MS)

+

+

+

+

i

?

+

+

?

+

+

o

+

+

+

+

+

Staph aureus FR

?

?

?

-

?

-

?

-

+

-

-

?

?

?

?

?

?

Staph epidermadis

+

i

o

+

o

+

+

+

+

+

+

o

+

o

+

+

+

Staph coag neg FR

?

?

?

-

?

i

?

-

i

-

-

?

?

?

?

?

?

Strep, pyogenes

+

+

o

+

+

+

+

+

+

o

+

o

+

o

+

+

+

Strep, pneumo

+

+

+

+

+

+

+

+

+

+

i

o

+

+

+

+

+

Strep viridans

+

+

o

+

+

+

o

+

+

o

i

o

+

+

+

+

+

Enterococcus faecalis +

o

o

i

o

?

o

+

?

+

+

o

+

o

o

o

+

Bacillus cereus

o

o

+

o

+

?

+

+

?

+

?

o

o

o

i

+

+

E. coli

o

+

+

+

o

+

+

+

+

+

+

+

+

+

+

+

o

H.influenzea

o

+

+

+

i

+

+

+

+

+

+

o

+

+

+

+

o

Klebsiella

o

+

+

-

o

+

+

+

+

+

i

+

+

+

+

+

o

Enterobacter

o

o

+

+

o

+

+

+

+

+

+

+

+

+

o

+

APPENDIX 1. TOPICAL ANTIBACTERIAL SPECTRUM (continued)

Table compiled from information from Physicians' Desk Reference for Ophthalmology, 2nd ed. Montvale, NJ: Medical Economics, 1999; Sanford JP, Gilbert, DN, Sande MA. Sanford Guide to Antimicrobial Therapy. Dallas: Antimicrobial Therapy, Inc., 1995; Gilman, AG, Rail, TW. Nies, AS, Taylor P. Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed. Oxford: Pergamon Press, 1990; Murray PR, Baron EJ, Pfaller, MA, Tenover FC, Yoken, RH. Manual of Clinical Microbiology, 6th ed. Washington, DC: American soceity for Microbiology press, 1995; Graves A et al. Cornea 2001:3:301-305; Kowalski RP et al. Am J Ophthalmol 2003:136:500-505; Hwang DG. Surv Ophthalmol 2004;49:S79-S83; Mather R et al. Am J Ophthalmol 2002:133:463-466; Fiscella RG et al. Ophthalmology 1999;106:2286-2290.