Listing Of Rigid Lens Products By Category A Daily Cleaners

Name Preservative Notes

Boston Advance® Cleaner Preservative free Not for direct use in eye

Boston® Cleaner Preservative free Not for direct use in eye

Claris Cleaning & Soaking Solution Unknown

Concentrated Cleaner Unknown

Non-Allergenic Clear Clean Sorbic acid Made by Contex: sold only to practitioners

Opti-Clean II® Polyquad Not for direct use in eye; approved for

Optimum by Lobob Extra Strength

Cleaner Perma-Brite

Polish Brite/Super Cleaner Non-

Allergenic RESOLVE/GP® Daily Cleaner Sereine™ Cleaner

Serine Soaking & Cleaning

Unknonwn

Not available Sorbic acid

Preservative free

Edetate disodium 0.1%, & Benzalkonium chloride 0.01% Unknown

PMMA lenses only

Made by Danker Laboratories Inc. Made by Contex: sold only to practitioners

Not for direct use in eye Not for direct use in eye

Not for direct use in eye

B. Enzymatic Cleaners

Name

Preservative

Active Ingredients

Notes

Boston® One Step Liquid Enzymatic Cleaner PROFREE/GP® Weekly Enzymatic Cleaner

Preservative free Edetate disodium

Subtilisin Papain

Not to be dissolved in distilled water

C. Daily Protein Remover

Name

Preservative

Notes

Opti-Free® Supraclens® Daily Protein Remover

Preservative free

Not for direct use in eye

D. Oxidation Systems

Name

Preservative

Notes

AOSEPT Clear Care Cleaning & Disinfection Solution

3% Hydrogen peroxide

E. Storage & Disinfection

Name

Preservative

Notes

BOSTON Advance® Comfort Formula Conditioning Solution Edetate disodium 0.05%,

Polyaminopropyl biguanide 0.0005%, Chlorhexadine gluconate 0.003% BOSTON® Conditioning Solution Edetate disodium 0.05%, Chlorhexidine

Gluconate 0.006%

Barnes-Hind ComfortCare® GP Wetting & Soaking Solution Edetate disodium 0.02% &

Chlorhexidine gluconate 0.005%

Claris Cleaning & Soaking Solution Benzyl alcohol 0.39% and Trisodium Not for direct use in eye

Edetate 0.5%

Sereine™ Wetting and Soaking Solution Edetate disodium 0.1% &

Benzalkonium chloride 0.01% WET-N-SOAK PLUS® Edetate disodium and Benzalkonium

Chloride 0.003%

Wetting & Soaking Solution Bausch & Lomb

F. Wetting/Rewetting

Name Preservative Notes

AQuify Long Lasting Comfort Drops

Not available

Blink contacts

Not available

CIBA Vision Lens Drops

Not available

Clerz Plus Lens Drops

Not available

Complete Blink-N-Clean Lens Drops

Not available

BOSTON® Rewetting Drops

Edetate disodium 0.05% &

Chlorhexadine gluconate 0.006%

CLARIS™ Rewetting Drops

Hydroxyethyl cellulose, polixetonium chlorine 0.006%

Optimum by Lobob Wetting & Rewetting Drops

Edetate disodium, sorbic acid, benzyl alcohol

Perma-Cote

Benzalkonium chloride 0.002%

Sereine™ Wetting Solution

Edetate disodium 0.1% &

Benzalkonium chloride 0.01%

TheraTears Contact Lens Comfort Drops

Not available

G. Combination Solutions

Name Preservative Notes

BOSTON Simplicity® Multi-Action Solution

Edetate disodium 0.05%,

Polyaminopropyl biguanide 0.0005%,

Chlorhexadine gluconate 0.003%

BOSTON Simplus Multi-Action Solution

Not available

Lens Comfort Multipurpose Solution

Not available

Optimum by Lobob C/D/S

Not available

Unique-pH Multi-Purpose Solution

Not available

APPENDIX 1. TOPICAL ANTIBACTERIAL SPECTRUM

Legend: + =

sensitive

baci

=

bacitracin

gati

=

gatifloxacin

oflox

= ofloxacin

o =

not sensitive

CAM

=

chloramphenicol

gent

=

gentamicin

poly/trimeth

= polymyxin B/trimethoprim

i =

intermediate activity

cipro

=

ciprofloxacin

levo

=

levofloxacin

sulfa

= sulfacetamide

? =

unknown

ceph

=

cephazolin

norflox =

norfloxacin

tetra/poly

= tetracycline/polymyxin B

erythro =

erythromycin

moxi

=

moxifloxacin

tobra

= tobramycin

FR = fluoroquinolone resistant

vaneo

= vancomycin

polymyxin poly/

tetra/

baci

cephazolin

CAM

cipro

erythro gati

gent

levo

moxi

norflox oflox

B

trimeth

sulfa

poly

tobra

vaneo

Staph aureus (MS)

+

+

+

+

i

?

+

+

?

+

+

o

+

+

+

+

+

Staph aureus FR

?

?

?

-

?

-

?

-

+

-

-

?

?

?

?

?

?

Staph epidermadis

+

i

o

+

o

+

+

+

+

+

+

o

+

o

+

+

+

Staph coag neg FR

?

?

?

-

?

i

?

-

i

-

-

?

?

?

?

?

?

Strep, pyogenes

+

+

o

+

+

+

+

+

+

o

+

o

+

o

+

+

+

Strep, pneumo

+

+

+

+

+

+

+

+

+

+

i

o

+

+

+

+

+

Strep viridans

+

+

o

+

+

+

o

+

+

o

i

o

+

+

+

+

+

Enterococcus faecalis +

o

o

i

o

?

o

+

?

+

+

o

+

o

o

o

+

Bacillus cereus

o

o

+

o

+

?

+

+

?

+

?

o

o

o

i

+

+

E. coli

o

+

+

+

o

+

+

+

+

+

+

+

+

+

+

+

o

H.influenzea

o

+

+

+

i

+

+

+

+

+

+

o

+

+

+

+

o

Klebsiella

o

+

+

-

o

+

+

+

+

+

i

+

+

+

+

+

o

Enterobacter

o

o

+

+

o

+

+

+

+

+

+

+

+

+

o

+

APPENDIX 1. TOPICAL ANTIBACTERIAL SPECTRUM (continued)

baci

cephazolin

CAM

cipro

erythro

gati

gent

levo

moxi

norflox

oflox

polymyxin B

poly/ trimeth

sulfa

tetra/ poly

tobra

vaneo

Moraxella species

o

+

+

+

o

+

o

+

+

o

+

o

o

o

o

o

o

Neisseria species

+

+

+

+

+

+

+

+

+

+

+

o

o

o

o

+

i

Pseud, aeruginosa

o

o

+

+

o

+

+

+

+

o

+

i

i

i

+

+

o

Pseud aeruginosa FR

?

?

?

-

?

-

?

-

-

-

-

?

?

?

?

?

?

Serratia marcescens

o

o

+

+

o

+

+

+

+

o

+

o

+

o

o

+

o

Aeromonas

o

o

i

+

o

+

+

+

+

+

+

o

o

o

o

o

o

Acinetobacter

+

o

o

+

o

+

+

+

+

+

+

i

o

o

o

+

o

Bacteroides fragilis

o

o

+

o

o

+

o

+

+

o

+

o

o

o

o

o

o

Proprionobacter acnes

o

o

o

o

i

o

o

o

o

o

i

o

+

Table compiled from information from Physicians' Desk Reference for Ophthalmology, 2nd ed. Montvale, NJ: Medical Economics, 1999; Sanford JP, Gilbert, DN, Sande MA. Sanford Guide to Antimicrobial Therapy. Dallas: Antimicrobial Therapy, Inc., 1995; Gilman, AG, Rail, TW. Nies, AS, Taylor P. Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed. Oxford: Pergamon Press, 1990; Murray PR, Baron EJ, Pfaller, MA, Tenover FC, Yoken, RH. Manual of Clinical Microbiology, 6th ed. Washington, DC: American soceity for Microbiology press, 1995; Graves A et al. Cornea 2001:3:301-305; Kowalski RP et al. Am J Ophthalmol 2003:136:500-505; Hwang DG. Surv Ophthalmol 2004;49:S79-S83; Mather R et al. Am J Ophthalmol 2002:133:463-466; Fiscella RG et al. Ophthalmology 1999;106:2286-2290.

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