Specific Tests

The exceptions to the lack of "specific" markers of drug hepatotoxicity are the detection of liver-kidney microsomal type 2 (anti-P450 2C9) antibodies in tienilic acid-induced hepatitis, antimito-chondrial type 6 antibody in iproniazid-induced hepatitis (Homberg et al., 1985), and liver microsomal antibody (anti-P450 1A2) in dihydralazine-related liver injury (Bourdi et al., 1990). Both tienilic acid and iproniazid were withdrawn because of the high incidence of hepatotoxicity, and dihydralazine is rarely used now in clinical practice.

Drug Free Life

Drug Free Life

How To Beat Drugs And Be On Your Way To Full Recovery. In this book, you will learn all about: Background Info On Drugs, Psychological Treatments Statistics, Rehab, Hypnosis and Much MORE.

Get My Free Ebook


Post a comment