The prescription data were therefore analysed and the mean number of injections or tablets (100 mg equivalent) per patient per six-month interval was calculated. The results for those patients who had used injections only are shown in Table 27.8 over a period of eight intervals and an increase was demonstrated at each interval. The first interval was omitted because it would be a trial period of use and for many patients may not be typical of later use. The latest interval was also excluded because it may not have been complete. The slope of the changes was statistically significant for both the injections and the tablets, but the changes were more marked for the injections. There were no identifiable confounders (Coulter, DM, presentation at the 18th Annual Meeting of National Centres Participating in the WHO International Drug Monitoring Programme, Portugal, 1996).

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