As for incidence rates, the number of cases reported during a given period of time is standardized for the corresponding person-time denominator. For example, if 18 cases of severe neutropenia have been reported for a cumulative exposure time (estimated from sales statistics) of 87 719 months, the reporting rate is: 18/87 719 = 2.05 for 10 000 person-months
Table 21.1. 95% confidence limits, two-sided, left and right one-sided, for m according to the Poisson distribution. To estimate the CI of a proportion p, bounds are divided by N. For a left one-sided interval, the upper bound of np is +i and of p is 1. For a right one-sided interval, the lower bound of np is —i and that of p is 0 (computations made by the author by using a HP 49G calculator).
Table 21.1. 95% confidence limits, two-sided, left and right one-sided, for m according to the Poisson distribution. To estimate the CI of a proportion p, bounds are divided by N. For a left one-sided interval, the upper bound of np is +i and of p is 1. For a right one-sided interval, the lower bound of np is —i and that of p is 0 (computations made by the author by using a HP 49G calculator).
m |
Two-sided |
Left one-sided |
Right one-sided |
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