Conclusion

Pharmacovigilance has to be conducted with the realization that behind every adverse reaction report there is a patient's face and one seeks to avoid that face reflecting the effects of serious iatrogenic disease. Table 36.5 and the data given above suggest that this has been largely achieved in respect of haemopoietic ADRs associated with the use of phenylbutazone. In the United Kingdom the ADROIT database facilitates continued observation to preserve and augment this type of improvement.

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