Co-operation with organisations interested in developing early signals of significance is of importance to achieve a safer drug therapy. The International Society for Pharmacoepidemiology (ISPE) is specifically interested in the science of pharmacovigilance and the CIOMS is pivotal in bringing interested parties together to mount various collaborative projects. Much support has been given to the International Society of Phar-macovigilance (ISOP) which is gaining increasing international status. The Centre also supports the European Pharmacovigilance Research Group which has allowed regulators and drug safety specialists from a variety of European countries to come together to plan co-ordinated drug safety exercises. Initiatives like these may pave the way for a much more logical development and investigation of drug safety signals world-wide.
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