Table of Contents

Introduction 223

Prodrugs and drug-like properties 224

What have you done for me recently? 226

This Paper 229

Recently Approved Prodrugs 229

Prostaglandin analogs 229

Antivirals with poor GIT permeability 230

Other polar drug examples 232

Water soluble prodrugs of poorly soluble drugs 233

It Takes a Team to Develop a Successful Prodrug Program 234

Conclusion 237

References 238

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