Table of Contents

Introduction 153

MiMBA 153

Solubilization 154

Absorption 155

Dissolution 156

Fraction Absorbed 157

Biopharmaceutics Landscape 158

Role of Dose on Oral Exposure 158

Regions of Limited Bioavailability 159

Estimating An, Dn, and Do Values 160

Formulation Strategy 161

Dissolution Limited 161

Solubility Limited 163

Permeability Limited 164

Summary 165

References 166

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