Breathing Pattern

The rate of breathing and depth of breathing also influence drug deposition in the airways. Rapid, shallow inspiration promotes central deposition of a drug, whereas slow, deep inspiration leads to peripheral airway deposition [4]. Furthermore, the rate of ventilation and tidal volume (volume of air inspired each breath) determines the residence time of the drug in the lungs, that is, the period in which the airways are exposed to drug [1]. Holding one's breath at the end of inspiration of an aerosol promotes deposition through sedimentation (by gravitation) and diffusion.

Coping with Asthma

Coping with Asthma

If you suffer with asthma, you will no doubt be familiar with the uncomfortable sensations as your bronchial tubes begin to narrow and your muscles around them start to tighten. A sticky mucus known as phlegm begins to produce and increase within your bronchial tubes and you begin to wheeze, cough and struggle to breathe.

Get My Free Ebook


Post a comment