Aerosolized Pentamidine Therapy For Active Pneumocystis Carinii Pneumonia

The overall rate of PCP prophylaxis failure has decreased significantly since 1995, coincident with the era of highly active antiretroviral therapy (HAART) [20].

Four pilot and three controlled studies using aerosolized pentamidine were conducted (Tables 1 and 2) [17,18,21-23]. Montgomery et al. [18] studied one group of AIDS patients with PCP who had received no prior therapy [18] and a second group that was intolerant to standard therapy [22]. Of the 25 patients, 23 recovered. Relapses occurred in only three patients during a mean follow-up of more than 1 year. No adverse systemic reactions were observed with aerosolized

Table 1 Aerosolized Pentamidine Studies for Mild-to-Moderate PCP in Patients with AIDS

Study group

n

Nebulizer type

ADR requiring drug change

(%)

(%)

Ref.

First episode

Dealing With Asthma Naturally

Dealing With Asthma Naturally

Do You Suffer From ASTHMA Chronic asthma is a paralyzing, suffocating and socially isolating condition that can cause anxiety that can trigger even more attacks. Before you know it you are caught in a vicious cycle Put an end to the dependence on inhalers, buying expensive prescription drugs and avoidance of allergenic situations and animals. Get control of your life again and Deal With Asthma Naturally

Get My Free Ebook


Post a comment