Otitis Externa Pseudomonas gram negatives proteus

-Polymyxin B/neomycin/hydrocortisone (Cortisporin otic susp or solution) 2-4 drops in ear canal tid-qid x 5-7 days.

[otic soln or susp per mL: neomycin sulfate 5 mg; polymyxin B sulfate 10,000 units; hydrocortisone 10 mg in 10 mL bottles)].

The suspension is preferred. The solution should not be used if the eardrum is perforated. Malignant Otitis Externa in Diabetes (Pseudomonas): -Ceftazidime (Fortaz) 100-150 mg/kg/day IV/IM q8h, max 12gm/day OR -Piperacillin (Pipracil) or ticarcillin (Ticar) 200-300

mg/kg/day IV/IM q4-6h, max 24gm/day OR -Tobramycin (Nebcin)

30 days-5 year: 7.5 mg/kg/day IV/IM q8h. 5-10 year: 6.0 mg/kg/day IV/IM q8h. >10 year: 5.0 mg/kg/day IV q8h.

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