Figure 5.3. (a) Electrospun PLGA fibers from melt (15 kV 7.5 cm electrode distance) and (b) relationship of electrode distance and diameter of DNA [27]. The mechanical properties of the nonwoven product were tested as well as the structural integrity of the delivered plasmid DNA over 20 days. These results demonstrate that electrospun PLGA is promising as a preliminary candidate for DNA release for gene therapy.

Electrode distance [cm]

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