Conclusions

Dengue and other flaviviruses have probably somewhere between four and six drug targets in their genome. History and drugability arguments suggest that NS5 polymerase is most likely to yield a drug in the near future, since chemical starting points are available and the optimization should be reasonably straight forward. It is likely that inhibitors of this target class will have broad spectrum activity and will therefore also be useful for other flaviviral diseases.

RdRp o

RdRp

SPA Bead

SPA Bead

SPA Bead

RdRp with inhibitor

SPA Bead

RdRp with inhibitor

Was this article helpful?

0 0
Swine Influenza

Swine Influenza

SWINE INFLUENZA frightening you? CONCERNED about the health implications? Coughs and Sneezes Spread Diseases! Stop The Swine Flu from Spreading. Follow the advice to keep your family and friends safe from this virus and not become another victim. These simple cost free guidelines will help you to protect yourself from the swine flu.

Get My Free Ebook


Post a comment