pedigree carrier genetic disorder polygenic complex character multiple allele codominance incomplete dominance sex-influenced trait Huntington's disease amniocentesis chorionic villi sampling genetic counseling gene therapy figure 12-9

This pedigree for cystic fibrosis (CF) shows that each of the two affected individuals in the sixth generation has unaffected parents. Note that a cystic fibrosis allele from the first generation passed unexpressed through the next four generations. Marriages within the family during those four generations resulted in affected individuals who had two copies of the recessive disease allele for the CF gene.

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