The respiratory system involves both external respiration and internal respiration. External respiration is the exchange of gases between the atmosphere and the blood. Internal respiration is the exchange of gases between the blood and the cells of the body. Once oxygen is in the cells, the cells use it to break down glucose and make ATP by the process of aerobic respiration. Without oxygen, the body could not obtain enough energy from food to survive. Excess carbon dioxide produced as a waste product of aerobic respiration is toxic to cells and is removed from the cells by internal respiration.

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