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CAUTION Sharp or pointed objects may cause injury. Handle pushpins carefully.

Insert a pushpin midway along the length of each straw segment of one color, as shown in the figure below. Push a paper clip into one end of each straw segment until the clip touches the pin.

2. Keeping the pins in a straight line, insert the paper clip from a blue-pushpin segment into the open end of a red-pushpin segment. Add additional straw segments to the red-segment end in the following order: green, yellow, blue, yellow, blue, yellow, green, red, red, and green. Use the permanent marker to label the blue-segment end "top." This chain of segments is one-half of your first model.

3. Assign nucleotides to the corresponding pushpin colors as follows: red = adenine, blue = guanine, yellow = cytosine, and green = thymine.

4. Construct the other half of your first model. Begin with a yellow segment across from the blue pushpin at the top of your first model. Keep the pins in a straight line. Link segments together in this second strand of DNA according to the base-pairing rules.

5. When you have completed your model of one DNA segment, make a sketch of the model in your lab report. Use colored pencils or pens to designate the pushpin colors. Include a key that indicates which nucleotide each color represents in your sketch.

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