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figure 7-9

Glycolysis yields two molecules of pyruvic acid. In aerobic respiration, each molecule of pyruvic acid reacts with coenzyme A (CoA) to form a molecule of acetyl CoA. Notice that CO2, NADH, and H+ are also produced in this reaction.

figure 7-9

Glycolysis yields two molecules of pyruvic acid. In aerobic respiration, each molecule of pyruvic acid reacts with coenzyme A (CoA) to form a molecule of acetyl CoA. Notice that CO2, NADH, and H+ are also produced in this reaction.

When pyruvic acid enters the mitochondrial matrix, it reacts with a molecule called coenzyme A to form acetyl (uh-SEET-uhl) coenzyme A, abbreviated acetyl CoA (uh-SEET-uhl KOH-AY). This reaction is illustrated in Figure 7-9. The acetyl part of acetyl CoA contains two carbon atoms, but as you learned earlier, pyruvic acid is a three-carbon compound. The carbon atom that is lost in the conversion of pyruvic acid to acetyl CoA is released in a molecule of CO2. This reaction reduces a molecule of NAD+ to NADH.

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