How many ATP molecules are made in cellular respiration? Refer to Figure 7-12 as you calculate the total. Recall that glycolysis and the Krebs cycle each produce two ATP molecules directly for every glucose molecule that is oxidized. Furthermore, each NADH molecule that supplies the electron transport chain can generate three ATP molecules, and each FADH2 molecule can generate two ATP molecules. Thus, the 10 NADH and two FADH2 molecules made through glycolysis, conversion of pyruvic acid to acetyl CoA, and the Krebs cycle can produce up to 34 ATP molecules by the electron transport chain and chemiosmosis. Adding the four ATP molecules from glycolysis and the Krebs cycle gives a maximum yield of 38 ATP molecules per molecule of glucose.
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