Breast Cancer

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Early results with ferumoxtran-10 MRI in breast cancer show a sensitivity of 78%, a specificity of 96% and a negative predictive value of 97% (Figure 3.4) (Michel et al. 2002). The sentinel lymph node procedure in breast cancer has a 3% to 10% false negative rate; furthermore, positive internal mammary lymph nodes are missed in 17%. Finally, the sentinel lymph node is the only positive node in 61% lymph node positive patients. These patients all undergo axillary dissection, with subsequent high rate of clinically significant lymph edema. As a result from its high negative predictive value, in patients with a negative ferumoxtran-10 MRI, axillary dissection may potentially be avoided. Further studies are under its way to validate this statement.

Figure 3.4. A 55-year-old patient with breast cancer and positive lymph node. Sagittal post-ferumoxtran-10 T2*-weighted MEDIC MR image shows one white (circle) and two dark nodes (arrows). The white node showed metastases on histopathology, the dark ones were normal.

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10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

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