The assessment of nodal status is an important aspect of staging patients with NSCLC. Anatomic imaging techniques such as CT and MR, which rely primarily upon nodal size, are limited by poor sensitivity and specificity. Recent advances in physiologic imaging with FDG PET have resulted in improved accuracy, which can be further enhanced by correlation with CT images. At present, a combined anatomic and physiologic approach using CT and FDG PET is the most accurate and cost-effective imaging method for determining nodal status in NSCLC patients.

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