There is no diagnostic test. Investigations only support the clinical suspicion. Neurophysiological: may detect a second asymptomatic lesion (see page 52).

1. Visual evoked potential (VEP). In optic nerve involvement the latency of the large positive wave is delayed beyond 110 msec. The amplitude of the waves may also be reduced.

2. Somatosensory evoked response (SSEP) may detect central sensory pathway lesions.

3. Brain stem auditory evoked potential (BAEP) may detect brain stem lesions.

Normal response - latency <110 msec

Abnormal response latency prolonged.

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