Nutritional deficiency presents a major problem in the developing world. In Western countries, alcoholism is the major cause of the neurological syndromes resulting from dietary deficiency with faddism and malabsorption disorders accounting for only a small number.
Vitamins appear important nutrients and certain disorders such as Wernicke Korsakoff syndrome (thiamine) or subacute combined degeneration (vit. Bi2) are attributed to a single deficiency. Others such as polyneuropathy result from multiple deficiency.
Vitamin deficiency in itself does not always produce symptoms; a dietary excess of carbohydrate seems essential for the development of the neurological features of thiamine deficiency.
As a rule, nutritional disorders of the nervous system present clinically in a symmetrical manner.
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