Chronic alcoholism Hyperemesis Carcinoma Renal dialysis Anorexia nervosa
Thiamine deficiency arising from poor nutrition Thiamine is an important coenzyme in the Kreb's cycle. Deficiency results in reduced cerebral metabolism, axonal conduction, synaptic transmission and DNA synthesis.
N.B. Korsakoffs psychosis may also be caused by head injury, anoxia, epilepsy, encephalitis and vascular diseases.
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