Oral contraceptives
A. Oral contraceptives have a failure rate of only 3 percent.OCPs have been associated with decreased risks of endometrial and ovarian cancers, benign breast disease, ectopic pregnancy and dysmenorrhea.
Hormonal Content of Selected Oral Contraceptives | ||||
Oral contraceptive |
Estrogen and progestin content |
Constant estrogen dose |
Constant progestin dose |
Generation |
Monophasic agents | ||||
Alesse (available as Alesse-21 or Alesse-28) |
20 mcg ethinyl estradiol, 0.1 mg levonorgestrel |
Yes |
Yes |
Second |
Loestrin (available as Loestrin 21 1/20 or Loestrin Fe 1/20) |
20 mcg ethinyl estradiol, 1.0 mg norethindrone acetate |
Yes |
Yes |
First |
Desogen |
30 mcg ethinyl estradiol, 0.15 mg desogestrel |
Yes |
Yes |
Third |
Levlen |
30 mcg ethinyl estradiol, 0.15 mg levonorgestrel |
Yes |
Yes |
Second |
Lo/Ovral |
30 mcg ethinyl estradiol, 0.3 mg norgestrel |
Yes |
Yes |
First |
Nordette |
30 mcg ethinyl estradiol, 0.15 mg levonorgestrel |
Yes |
Yes |
Second |
Ortho-Cept |
30 mcg ethinyl estradiol, 0.15 mg desogestrel |
Yes |
Yes |
Third |
Brevicon |
35 mcg ethinyl estradiol, 0.5 mg norethindrone |
Yes |
Yes |
First |
Demulen 1/35 |
35 mcg ethinyl estradiol, 1.0 mg ethynodiol diacetate |
Yes |
Yes |
First |
Modicon |
35 mcg ethinyl estradiol, 0.5 mg norethindrone |
Yes |
Yes |
First |
Norethin 1/35E |
35 mcg ethinyl estradiol, 1.0 mg norethindrone |
Yes |
Yes |
First |
Norinyl 1+35 |
35 mcg ethinyl estradiol, 1.0 mg norethindrone |
Yes |
Yes |
First |
Ortho-Cyclen |
35 mcg ethinyl estradiol, 0.25 mg norgestimate |
Yes |
Yes |
Second |
Ortho-Novum 1/35 |
35 mcg ethinyl estradiol, 1.0 mg norethindrone |
Yes |
Yes |
First |
Ovcon-35 |
35 mcg ethinyl estradiol, 0.4 mg norethindrone |
Yes |
Yes |
First |
Demulen 1/50 |
50 mcg ethinyl estradiol, 1.0 mg ethynodiol diacetate |
Yes |
Yes |
First |
Oral contraceptive |
Estrogen and progestin content |
Constant estrogen dose |
Constant progestin dose |
Generation |
0vcon-50 |
50 mcg ethinyl estradiol, 1.0 mg norethindrone |
Yes |
Yes |
First |
Ovral |
50 mcg ethinyl estradiol, 0.5 mg norgestrel |
Yes |
Yes |
First |
Norinyl 1+50 |
50 mcg mestranol, 1.0 mg norethindrone |
Yes |
Yes |
First |
Ortho-Novum 1/50 |
50 mcg mestranol, 1.0 mg norethindrone |
Yes |
Yes |
First |
Triphasic agents | ||||
Ortho-Novum 7/7/7 |
35 mcg ethinyl estradiol, 0.5/0.75/1.0 mg norethindrone |
Yes |
No |
First |
Ortho Tri-Cyclen |
35 mcg ethinyl estradiol, 0.18/0.215/0.25 mg norgestimate |
Yes |
No |
Second |
Tri-Norinyl |
35 mcg ethinyl estradiol, 0.5/1.0/0.5 mg norethindrone |
Yes |
No |
First |
Tri-Levlen |
30/40/30 mcg ethinyl estradiol, 0.05/0.075/0.125 mg levonorgestrel |
No |
No |
Second |
Triphasil |
30/40/30 mcg ethinyl estradiol, 0.05/0.075/0.125 mg levonorgestrel |
No |
No |
Second |
Estrogen phasic agent | ||||
Estrostep (Estrostep 21 or Estrostep Fe) |
20/30/35 mcg ethinyl estradiol, 1 mg norethindrone |
No |
Yes |
First |
Progestin-only agents | ||||
Micronor |
0.35 mg norethindrone |
None |
Yes |
Not applicable |
Nor-QD |
0.35 mg norethindrone |
None |
Yes |
Not applicable |
Ovrette |
0.075 mg norgestrel |
None |
Yes |
Not applicable |

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