Oral contraceptives

A. Oral contraceptives have a failure rate of only 3 percent.OCPs have been associated with decreased risks of endometrial and ovarian cancers, benign breast disease, ectopic pregnancy and dysmenorrhea.

Hormonal Content of Selected Oral Contraceptives

Oral contraceptive

Estrogen and progestin content

Constant estrogen dose

Constant progestin dose

Generation

Monophasic agents

Alesse (available as Alesse-21 or Alesse-28)

20 mcg ethinyl estradiol, 0.1 mg levonorgestrel

Yes

Yes

Second

Loestrin (available as Loestrin 21 1/20 or Loestrin Fe 1/20)

20 mcg ethinyl estradiol, 1.0 mg norethindrone acetate

Yes

Yes

First

Desogen

30 mcg ethinyl estradiol, 0.15 mg desogestrel

Yes

Yes

Third

Levlen

30 mcg ethinyl estradiol, 0.15 mg levonorgestrel

Yes

Yes

Second

Lo/Ovral

30 mcg ethinyl estradiol, 0.3 mg norgestrel

Yes

Yes

First

Nordette

30 mcg ethinyl estradiol, 0.15 mg levonorgestrel

Yes

Yes

Second

Ortho-Cept

30 mcg ethinyl estradiol, 0.15 mg desogestrel

Yes

Yes

Third

Brevicon

35 mcg ethinyl estradiol, 0.5 mg norethindrone

Yes

Yes

First

Demulen 1/35

35 mcg ethinyl estradiol, 1.0 mg ethynodiol diacetate

Yes

Yes

First

Modicon

35 mcg ethinyl estradiol, 0.5 mg norethindrone

Yes

Yes

First

Norethin 1/35E

35 mcg ethinyl estradiol, 1.0 mg norethindrone

Yes

Yes

First

Norinyl 1+35

35 mcg ethinyl estradiol, 1.0 mg norethindrone

Yes

Yes

First

Ortho-Cyclen

35 mcg ethinyl estradiol, 0.25 mg norgestimate

Yes

Yes

Second

Ortho-Novum 1/35

35 mcg ethinyl estradiol, 1.0 mg norethindrone

Yes

Yes

First

Ovcon-35

35 mcg ethinyl estradiol, 0.4 mg norethindrone

Yes

Yes

First

Demulen 1/50

50 mcg ethinyl estradiol, 1.0 mg ethynodiol diacetate

Yes

Yes

First

Oral contraceptive

Estrogen and progestin content

Constant estrogen dose

Constant progestin dose

Generation

0vcon-50

50 mcg ethinyl estradiol, 1.0 mg norethindrone

Yes

Yes

First

Ovral

50 mcg ethinyl estradiol, 0.5 mg norgestrel

Yes

Yes

First

Norinyl 1+50

50 mcg mestranol, 1.0 mg norethindrone

Yes

Yes

First

Ortho-Novum 1/50

50 mcg mestranol, 1.0 mg norethindrone

Yes

Yes

First

Triphasic agents

Ortho-Novum 7/7/7

35 mcg ethinyl estradiol, 0.5/0.75/1.0 mg norethindrone

Yes

No

First

Ortho Tri-Cyclen

35 mcg ethinyl estradiol, 0.18/0.215/0.25 mg norgestimate

Yes

No

Second

Tri-Norinyl

35 mcg ethinyl estradiol, 0.5/1.0/0.5 mg norethindrone

Yes

No

First

Tri-Levlen

30/40/30 mcg ethinyl estradiol, 0.05/0.075/0.125 mg levonorgestrel

No

No

Second

Triphasil

30/40/30 mcg ethinyl estradiol, 0.05/0.075/0.125 mg levonorgestrel

No

No

Second

Estrogen phasic agent

Estrostep (Estrostep 21 or Estrostep Fe)

20/30/35 mcg ethinyl estradiol, 1 mg norethindrone

No

Yes

First

Progestin-only agents

Micronor

0.35 mg norethindrone

None

Yes

Not applicable

Nor-QD

0.35 mg norethindrone

None

Yes

Not applicable

Ovrette

0.075 mg norgestrel

None

Yes

Not applicable

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