Clinical Manifestations

A. Acne comedones are usually found on the forehead and upper cheeks of adolescents. Comedones may progress to inflammatory lesions on the lower cheeks, chin, chest, upper back, and shoulders.

B. In females, the possibility of androgenic disorders such as polycystic ovarian disease and Cushing's syndrome should be considered. The patient should be asked about menstrual irregularities and should be examined for hirsutism.

C. Acne will often subside during the late teens. However, 20-50% of women seeking acne treatment are in their 20s, and a considerable number have persistent acne into the 30s, 40s, and even 50s.

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