Cluster 2 Psychologic or psychosocial symptoms

Depressed mood and/or Interest/pleasure reduction Guilt feelings Suicidal thoughts

Note: Diagnosis of major depression requires at least one of the first two symptoms under cluster 2 and four of the remaining symptoms to be present for at least two weeks. Symptoms should not be accounted for by bereavement.

II. Laboratory evaluation may include a complete blood cell count, chemistry panel, thyroid stimulating hormone, and glucose. An electrocardiogram is recommended if the patient is more than 40 years of age.

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