1. The lesions consists of grouped vesicles or a solitary vesicle with erythematous bases, progressing to ulceration. Primary infections may be accompanied by flu-like symptoms.
2. Prodromal burning or itching is present in recurrent disease.
3. Lesions are painful and persist for several days forming a honey-colored crust. Healing is usually complete within 3 weeks.
B. Immunosuppressed patients, especially HIV infected patients, have more frequent and more severe infections. Contact with ulcerative lesions or with secretions may result in transmission. Asymptomatic viral shedding may also cause infection.
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