In SSc, fibrosis occurs in various organs, especially the skin and esophagus. Concerning the pancreatic fibrosis in SSc, D'Angelo et al. studied 58 autopsies with SSc, coupled with the examination of 58 autopsy cases as controls . In the SSc autopsies, fibrosis occurred in 10 cases (17%), but the incidence of the fibrosis in SSc was almost the same (19%) as the incidence in control cases .
These findings indicated that SSc does not cause pancreatic fibrosis by itself. Although case reports of pancreatitis in SSc have been published in the literature, it is thought that overlapping of pancreatitis in SSc is exceedingly rare .
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