Hemosiderin deposition has been well investigated by many authors, such as in cases of diabetes mellitus, which is usually related to a deposition of hemosiderin in the B cells of the islets of Langerhans . Hemosiderin deposition occurs predominantly in the acinar tissue in cases of primary hemochromatosis (fig. 4) and in the periinsular acinar tissue in patients who receive a large volume of blood through transfusions [36, 37]. In the latter, the distribution and amount of hemosiderin increase in accordance with the volume of blood given. According to Rahier et al. , the histological appearance of the islets was normal as HE staining, their shape and size being unchanged; amyloid deposits were absent, as were atrophic islets. A severe reduction in the number of immunoreactive B cells was noted in the four diabetic patients. Under the electron microscope, iron deposits were restricted to B cells and associated with progressive loss of endocrine granules.
Hence, glucose intolerance is related to selective deposition of hemosiderin in B cells of the pancreas.
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All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.