Biopsy of the Papilla of Vater

Eighty-nine endoscopic biopsies of the papilla of Vater, ranging from 1 to 5 pieces with an average of 2.5 per case, were obtained from 55 patients with an average age of 59.6 (25-81) years during the study period, excluding pathologically diagnosed cases of ampullary carcinoma. The majority of patients were referred for the evaluation of suspected ampullary carcinoma.

Among the biopsied specimens, the ampullary mucosa, which consists of larger or hyperplastic and dilated glands with conspicuous goblet cells adjacent to

Ampullary Biopsy

Fig. 8. A biopsy specimen of ampullary mucosa (71 years, M). The ampullary mucosa on the right side of the figure and duodenal mucosa on the left side were taken together and were in contact without border. Note that the ampullary mucosa shows larger, hyperplastic and dilated glands, but not a papillary pattern. HE. X100. (Reproduced with permission from [7].)

Fig. 8. A biopsy specimen of ampullary mucosa (71 years, M). The ampullary mucosa on the right side of the figure and duodenal mucosa on the left side were taken together and were in contact without border. Note that the ampullary mucosa shows larger, hyperplastic and dilated glands, but not a papillary pattern. HE. X100. (Reproduced with permission from [7].)

the duodenal glands, was included in 43 out of the 55 cases without border along the duodenal mucosa (fig. 8) [7]. In the remaining 12 cases, only the duodenal mucosa was removed. When endoscopists try to remove specimens from the papilla of Vater, they may obtain pieces of tissue from the distended glands or so-called overreplacement mucosa and not from the intrapapillary portion. Hence, when only duodenal mucosa is removed by ampullary biopsy, no distended glands might be found or the endoscopist may have missed the papilla of Vater.

Was this article helpful?

0 0

Post a comment