In this chapter, chronic inflammation refers to chronic pancreatitis characterized by interlobular (perilobular) fibrosis presenting clinically as chronic alcoholic pancreatitis, and two kinds of complication of chronic inflammation are described: one is that caused by progression of the pancreatitis itself and the other by involvement of various anatomical structures. The former is represented by protein plugs and stones and by tumor-forming pancreatitis, the latter by involvement of the splenic vein, duodenum, intrapancreatic bile duct and colon.
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Because the pancreatic and peripancreatic anatomy is very complex, inflammation in the pancreas can easily spread to various anatomical structures in and around the pancreas and various kinds of complication can arise. In this chapter, the term 'chronic inflammation' refers to so-called chronic pancreatitis characterized not only by intralobular fibrosis but also by interlobular (perilobular) fibrosis (fig. 1) , usually presenting clinically as chronic alcoholic pancreatitis.
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