■ Figure 11-10 STR analysis by capillary gel electrophoresis. Instead of bands on a gel (top), peaks of fluorescence on an electropherogram reveal the PCR product sizes (bottom). Alleles are determined by comparison with molecular weight markers and allelic ladders run through the capillary simultaneously with the sample amplicons.
for example, TH01 is in intron 1 of the human tyrosine hydroxylase gene on chromosome 11, and TPOX is in intron 10 of the human thyroid peroxidase gene on chromosome 2. These STRs do not have any phenotypic effect with respect to these genes. Non-gene associated STRs are designated by the D#S# system. D stands for DNA, the following number designates the chromosome
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