A young man of 26 years reported to his doctor with joint pain and fatigue. Complete blood count and differential counts were indicative of chronic myeloge-nous leukemia. The diagnosis was confirmed by karyotyping, showing 9/20 metaphases with the t(9;22) translocation. Quantitative PCR was performed to establish a baseline for monitoring tumor load during and following treatment. Treatment with Gleevec and a bone marrow transplant were recommended. The man had a twin brother, who volunteered to donate bone marrow. The two brothers were not sure if they were fraternal or identical twins. Donor and recipient buccal cells were sent to the molecular pathology laboratory for STR informative analysis. The results are shown below.
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