1/1.31 X 1017

*AmpliSTR Identifiler Kit (Applied Biosystems) fPowerPlex Systems (Promega)

*AmpliSTR Identifiler Kit (Applied Biosystems) fPowerPlex Systems (Promega)

parison of results between laboratories. As described above, an STR locus genotype is defined by the number of repeats in the alleles. For instance, if the locus genotype in Figure 11-8 represented homologous chromosomes from an individual, the locus would be heterozygous, with 7 repeats on one chromosome and 8 repeats on the other. This locus would thus be designated 7/8 or 7,8. A homozygous locus (where both homologous chromosomes carry the same allele) is designated by the single number of repeats of that allele; for instance, 7/7 or 7,7. Some reports use a single number, such as 6 or 7 to designate a homozygous locus. Microvariant alleles containing partial repeat units are indicated by the number of complete repeats followed by a decimal point and then the number of bases in the partial repeat. For example, the 9.3 allele of the TH01 locus has 9 full 4-base pair repeat units and one repeat unit with 3 base pairs. Microvariants are detected as bands or peaks very close to the full-length allele (Fig. 11-13).

The genotype, or profile, of a specimen is the collection of alleles in all the locus genotypes tested. To determine the extent of certainty that one profile matches another, the occurrence of the detected genotype in the general or a defined population must be assessed.

A matching genotype is not necessarily an absolute determination of identity of an individual. Genetic concordance is a term used to express the situation where all locus genotypes (alleles) from two sources are the same. Concordance is interpreted as inclusion of a single individual as the donor of both genotypes. Two samples are

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