Overview Of Trophoblastic Subpopulations In Normal Placenta

Based on morphological, immunophenotypical, and functional studies, the trophoblast in villous and extravillous locations can be divided into three distinct populations: cytotrophoblast (CT), syncytiotrophoblast (ST), and intermediate trophoblast (IT) (1,2). The anatomical locations and functional aspects of each trophoblastic subpopulation are briefly summarized next.

From: Current Clinical Oncology: Molecular Pathology of Gynecologic Cancer Edited by: A. Giordano, A. Bovicelli, and R. Kurman © Humana Press Inc., Totowa, NJ

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